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de Saint Hilaire et al (2001) calculated arousal with EEG and local brain monoaminergic ranges working with microdialysis in the prefrontal cortex along with the ventromedial preoptic spot on the hypothalamus in rats supplied modafinil.Modafinil is applied to take care of extreme sleepiness due to slumber apnea, narcolepsy, or change operate slumbe